Bleeding and Clotting

Bleeding and Clotting Disorders Protocol:CSL627_3001 Condition or Disease: Hemophilia A Study Type: Interventional (Clinical Trial) Status: Open for enrollment Study Title: A Phase III Open Label, Multicenter, Extension Study to Assess the Safety and Efficacy of Recombinant Coagulation Factor VIII (rVIII SingleChain, CSL627) in Subjects with Severe Hemophilia A Principal I investigator: Joseph Lasky III,

Protocol:PRO15070638 Condition or Disease: Von Willebrand disease (vWD) Study Type: Interventional (Clinical Trial) Status: Opening Late 2018 Study Title: The VWD Minimize Menorrhagia (VWDMin) Trial Principal I investigator: Joseph Lasky III, MD

Bleeding and Clotting Disorders Protocol:ALN-AT3SC-003 Condition or Disease: Hemophilia A or B Study Type: Interventional (Clinical Trial) Status: Open for enrollment Study Title: ATLAS-INH: A Phase 3 Study to Evaluate the Efficacy and Safety of Fitusiran in Patients with Hemophilia A or B, with Inhibitory Antibodies to Factor VIII or IX Principal I investigator: Joseph

Bleeding and Clotting Disorders Protocol:ALN-AT3SC-004 Condition or Disease: Hemophilia A or B Study Type: Interventional (Clinical Trial) Status: Open for enrollment Study Title: ATLAS-A/B: A Phase 3 Study to Evaluate the Efficacy and Safety of Fitusiran in Patients With Hemophilia A or B, Without Inhibitory Antibodies to Factor VIII or IX Principal I investigator: Joseph

Bleeding and Clotting Disorders Protocol:1160.106 Condition or Disease: Venous thrombosis Study Type: Interventional (Clinical Trial) Status: Open for enrollment Study Title: Open-label, randomized, parallel-group, active-controlled, multi-centre, non-inferiority study of dabigatran etexilate versus standard of care for venous thromboembolism treatment in children from birth to less than 18 years of age: The DIVERSITY study Principal I

Bleeding and Clotting Disorders Protocol:1160.108 Condition or Disease: Venous Thromboembolism, Secondary Prevention Study Type: Interventional (Clinical Trial) Status: Open for enrollment Study Title: Open label, single arm safety prospective cohort study of dabigatran etexilate for secondary prevention of venous thromboembolism in children from 0 to less than 18 years Principal I investigator: Alan Ikeda, MD

Bleeding and Clotting Disorders Protocol:1321.7 Condition or Disease: Hemorrhage Study Type: Interventional (Clinical Trial) Status: Open for enrollment Study Title: Single dose, open label, uncontrolled, safety trial of intravenous administration of idarucizumab to paediatric patients enrolled from ongoing phase IIb/III clinical trials with dabigatran etexilate for the treatment and secondary prevention of venous thromboembolism. Principal

Bleeding and Clotting Disorders Protocol:GENA-99 Condition or Disease: Hemophilia A Study Type: Observational Status: Open for enrollment Study Title: Prospective, multinational, non-interventional post-authorisation study to document the long-term immunogenicity, safety, and efficacy of Human-cl rhFVIII (simoctocog alfa) in patients with haemophilia A treated in routine clinical practice Principal I investigator: Joseph Lasky III, MD More