Pediatric Hematology

What Is Pediatric Hematology?

Pediatric hematology is the study and treatment of blood diseases and blood-forming organs. These diseases include childhood cancer, sickle cell disease, anemia and other related hemoglobinopathies related to children. Cure 4 The Kids participates in research and clinical trials while offering care and treatment to infants, children, and adolescents with the latest information and options available. During the last 50 years, Pediatric Hematology has increasingly used immunology, biochemistry, enzymology, genetics and molecular genetics and others as we continue to search for a cure.

Dr. Aimee Foord
Director of C4K’s Bleeding & Clotting Program

What is Bleeding and Clotting Disorder?

A bleeding and clotting disorder is a condition that affects the way your blood normally clots. The clotting process, known as coagulation, changes blood from a liquid to a solid. When you’re injured, your blood normally begins to clot to prevent a massive loss of blood. Sometimes, certain conditions prevent blood from clotting properly, which can result in heavy or prolonged bleeding.

Bleeding disorders can cause abnormal bleeding both outside and inside the body. Some disorders can drastically increase the amount of blood leaving your body. Others cause bleeding to occur under the skin or in vital organs, such as the brain.


What Types of Bleeding and Clotting Disorders Are There?

Hemophilia A and B can causes heavy or unusual bleeding into the joints. Though hemophilia is rare, it can have life-threatening complications. Factor II, V, VII, X, or XII deficiencies are bleeding disorders related to blood clotting problems or abnormal bleeding problems, and Von Willebrand’s disease is the most common inherited bleeding disorder. It develops when the blood lacks von Willebrand factor, which helps the blood to clot.

Clinical Studies

What Causes a Bleeding and Clotting Disorder?

Bleeding disorders develop when the blood can’t clot properly. For blood to clot, your body needs blood proteins called clotting factors and blood cells called platelets. Normally, platelets clump together to form a plug at the site of a damaged or injured blood vessel. The clotting factors then come together to form a fibrin clot. This keeps the platelets in place and prevents blood from flowing out of the blood vessel.

For people with bleeding and clotting disorders, the clotting factors or platelets don’t work the way they should or are in short supply. When the blood doesn’t clot, excessive or prolonged bleeding can occur. It can also lead to spontaneous or sudden bleeding in the muscles, joints, or other parts of the body.

Bleeding and clotting disorders are largely inherited, which means they’re passed from a parent to their child. Some disorders may develop as a result of other medical conditions, such as liver disease.


Bleeding and Clotting Disorder Symptoms

Symptoms can vary depending on the specific type of bleeding and clotting disorder. The main signs may include unexplained and easy bruising, frequent nosebleeds, excessive bleeding from small cuts or an injury, or bleeding into joints.

Bleeding and Clotting
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We believe every child is entitled to the best treatment options that modern science has to offer. This is why we also place a great emphasis on raising money to support access to these trials for all children.